A methotrexate labelled dual metal oxide nanocomposite for long-lasting anti-cancer theranostics

A methotrexate labelled dual metal oxide nanocomposite for long-lasting anti-cancer theranostics

We explored the feasibility of a self-assembled chitosan nanocomposite incorporating cerium oxide/nanoceria and superparamagnetic iron oxide nanoparticles (Chit−IOCO NPs), conjugated with methotrexate (MTX) and Cy5 dye, as an integrated cancer theranostic nanosystem (Chit-IOCO-MTX-Cy5). In this syst...

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Bibliographic Details
Main Authors: Joyce L.Y. Tang, Shehzahdi S. Moonshi, Yuao Wu, Gary Cowin, Karla X. Vazquez- Prada, Huong D.N. Tran, Andrew C. Bulmer, Hang Thu Ta
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Materials Today Bio
Subjects:
Nanotheranostic
Chitosan
Cerium oxide
Nanoceria
Reactive oxygen species
Methotrexate
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004381
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