In Vitro and In Vivo Investigation of the Angiogenic Effects of Liraglutide during Islet Transplantation.

In Vitro and In Vivo Investigation of the Angiogenic Effects of Liraglutide during Islet Transplantation.

<h4>Introduction</h4>This study investigated the angiogenic properties of liraglutide in vitro and in vivo and the mechanisms involved, with a focus on Hypoxia Inducible Factor-1α (HIF-1α) and mammalian target of rapamycin (mTOR).<h4>Materials and methods</h4>Rat pancreatic i...

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Main Authors: Allan Langlois, Carole Mura, William Bietiger, Elodie Seyfritz, Camille Dollinger, Claude Peronet, Elisa Maillard, Michel Pinget, Nathalie Jeandidier, Séverine Sigrist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0147068&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0147068&type=printable

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