Optimizing in vitro spherulation cues in the fungal pathogen Coccidioides

Optimizing in vitro spherulation cues in the fungal pathogen Coccidioides

ABSTRACT Coccidioides spp. are part of a group of thermally dimorphic fungal pathogens, which grow as filamentous cells (hyphae) in the soil and transform to a different morphology upon inhalation into the host. The Coccidioides host form, the spherule, is unique and highly undercharacterized due to...

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Bibliographic Details
Main Authors: Christina M. Homer, Elena Ochoa, Mark Voorhies, Anita Sil
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mSphere
Subjects:
Coccidioides
fungal pathogenesis
arthroconidia
morphology
development
Online Access:https://journals.asm.org/doi/10.1128/msphere.00679-24
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