Structural basis for metal ion transport by the human SLC11 proteins DMT1 and NRAMP1

Abstract Iron and manganese are essential nutrients whose transport across membranes is catalyzed by members of the SLC11 family. In humans, this protein family contains two paralogs, the ubiquitously expressed DMT1, which is involved in the uptake and distribution of Fe2+ and Mn2+, and NRAMP1, whic...

Full description

Saved in:
Bibliographic Details
Main Authors: Márton Liziczai, Ariane Fuchs, Cristina Manatschal, Raimund Dutzler
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54705-0
Tags: Add Tag
No Tags, Be the first to tag this record!