Enhancement of immunogenicity of DNA vaccine against infectious bursal disease virus by co-delivery with oral vaccine encoding chicken interleukin-2

Mice and 14-day-old chickens were orally inoculated with the recombinant attenuated Salmonella typhimurium strain ZJ111 carrying pCI-IL-2 expression plasmid encoding the Interleukin II protein. The results showed the ZJ111/pCI-IL-2 was relatively safe. Fourteen-day-old non-immunized chickens were co...

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Bibliographic Details
Main Authors: XIE Rong-hui, WAN Wang-jun, LI Long, LI Jian-rong, YU Lian
Format: Article
Language:English
Published: Zhejiang University Press 2007-05-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/1008-9209.2007.03.0237
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