De novo assembly of RNA m6A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation

De novo assembly of RNA m6A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation

Summary: The factors that install and recognize N6-methyladenosine (m6A) on RNA to regulate gene expression are well characterized, but how their spatial organization responds to physiological stress, including infection, is unclear. Here, we show that human cytomegalovirus (HCMV) infection induces...

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Bibliographic Details
Main Authors: Rebecca C. Grande, Chia-Ching Lin, Michael Cammer, Ebube D. Emesom, Maaz Asher Khurram, Chris Boutell, Lance T. Denes, Timothée Lionnet, Angus C. Wilson, Ian Mohr
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725005972
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