Estimation of therapeutic threshold for tuberculosis using adapted nominal group technique and clinical vignettes in clinical and community settings in Southern Africa

Estimation of therapeutic threshold for tuberculosis using adapted nominal group technique and clinical vignettes in clinical and community settings in Southern Africa

Background: When confronted with diagnostic uncertainty and a decision on whether to start treatment or not, clinicians consider the potential harm and benefit of offering versus withholding treatment. Treatment can be offered if the probability of tuberculosis (TB) in the patient is above the “ther...

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Main Authors: Alfred Kipyegon Keter, Alastair Van Heerden, Tom Decroo, Tom Boyles, Shannon Bosman, Thandanani Madonsela, Lindani Innocent Msimango, Lenika Naiken, Carlos Kiyan, Mashaete Kamele, Irene Ayakaka, Klaus Reither, Bart Karl Mario Jacobs, Lutgarde Lynen
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Subjects:
Adapted nominal group technique
Therapeutic threshold
Clinical decision-making
Clinical vignettes
Tuberculosis
Diagnostic uncertainty
Online Access:http://www.sciencedirect.com/science/article/pii/S2405579425000208
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