Dopaminergic modulation of propofol-induced activation in VLPO neurons: the role of D1 receptors in sleep-promoting neural circuits

BackgroundThe ventrolateral preoptic nucleus (VLPO) is a crucial regulator of sleep, and its neurons are implicated in both sleep-wake regulation and anesthesia-induced loss of consciousness. Propofol (PRO), a widely used intravenous anesthetic, modulates the activity of VLPO neurons, but the underl...

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Bibliographic Details
Main Authors: Kun Qian, Yu Zhang, Yang Liu, Sisi Wu, Zikun Duan, Jianhao Liao, Wei Luo, Mo Zhou, Xuejiao Dou, Xingkui Liu, Tian Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1485873/full
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