Phase I clinical trial designs in oncology: A systematic literature review from 2020 to 2022

Abstract Background: Phase I clinical trials aim to find the highest dose of a novel drug that may be administrated safely without having serious adverse effects. Model-based designs have recently become popular in dose-finding procedures. Our objective is to provide an overview of phase I clinica...

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Bibliographic Details
Main Authors: Ning Li, Xitong Zhou, Donglin Yan
Format: Article
Language:English
Published: Cambridge University Press 2024-01-01
Series:Journal of Clinical and Translational Science
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2059866124005995/type/journal_article
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