Case Report: Falsely elevated PTH level in a young woman caused by immunoassay interference resulting from macro-PTH

Case Report: Falsely elevated PTH level in a young woman caused by immunoassay interference resulting from macro-PTH

Elevated parathyroid hormone (PTH) levels usually suggest an underlying parathyroid disorder. However, immunoassay interference, such as macro-PTH, can result in falsely elevated readings, leading to diagnostic inaccuracy. Here, we report the case of a 27-year-old woman with persistently elevated PT...

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Bibliographic Details
Main Authors: Giuseppe Perruolo, Lidia Santarpia, Cristina Morelli, Domenico Rendina, Federica Mormone, Giusy Ferraro, Pietro Formisano, Francesco Oriente
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Endocrinology
Subjects:
parathyroid hormone
macro-PTH
chemiluminescent immunoassay
analytical interference
polyethylene glycol
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1564352/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1564352/full

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