Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria–mucus interactions

Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria–mucus interactions

The intestinal mucosal barrier is a dynamic system that allows nutrient uptake, stimulates healthy microbe–host interactions, and prevents invasion by pathogens. The mucosa consists of epithelial cells connected by cellular junctions that regulate the passage of nutrients covered by a mucus layer th...

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Bibliographic Details
Main Authors: Evelien Floor, Jinyi Su, Maitrayee Chatterjee, Elise S. Kuipers, Noortje IJssennagger, Faranak Heidari, Laura Giordano, Richard W. Wubbolts, Silvia M. Mihăilă, Daphne A. C. Stapels, Yvonne Vercoulen, Karin Strijbis
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Mucus
air–liquid growth
ALI
VIP
transwell
gut-on-a-chip
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2434685
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https://www.tandfonline.com/doi/10.1080/19490976.2024.2434685

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