In silico analysis of ventricular action potential with a current–voltage‐time representation: Thresholds, membrane resistance, repolarization reserve

In silico analysis of ventricular action potential with a current–voltage‐time representation: Thresholds, membrane resistance, repolarization reserve

Abstract The waveform of ventricular action potential (AP) is a key determinant of the cardiac cycle, a marker of beating pathophysiology, and a target for anti‐arrhythmic drug design. The information contained in the waveform, though, is limited to the actual dynamics of the AP under consideration....

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Bibliographic Details
Main Author: Massimiliano Zaniboni
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Physiological Reports
Subjects:
cardiac action potential
membrane resistance during the action potential
quasi‐instantaneous IV curves
reserve of repolarization
threshold for all‐or‐none‐repolarization
threshold for excitation
Online Access:https://doi.org/10.14814/phy2.70085
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https://doi.org/10.14814/phy2.70085

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