A Bis-Glycosylamine Strategy for the Synthesis of Dimeric Iminosugars Based on a DAB-1 Scaffold

A Bis-Glycosylamine Strategy for the Synthesis of Dimeric Iminosugars Based on a DAB-1 Scaffold

A straightforward synthetic route towards DAB-1 scaffolded dimeric iminosugars is described here, starting from readily available bis-glycosylamines. The method allows the integration of a variety of linkages (aryl, alkyl, polyethyleneglycol chains) between both iminosugars through the choice of the...

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Bibliographic Details
Main Authors: Kamilia Ould Lamara, Nathan Noël, Fabien Massicot, Jean-Luc Vasse, Stéphane P. Vincent, Jean-Bernard Behr
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
iminosugars
multivalency
glycosylamines
glycosidases
inhibition
glycophanes
Online Access:https://www.mdpi.com/1420-3049/30/2/226
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