Small interfering RNA effect on lipoprotein(a): a systematic review

Small interfering RNA effect on lipoprotein(a): a systematic review

Abstract Background This systematic review investigates the effect of small interfering RNA (siRNA) therapies on lipoprotein(a) [Lp(a)] levels. The purpose is to evaluate the outcomes of recent randomized controlled trials (RCTs) involving siRNA treatments aimed at lowering Lp(a) levels, a known car...

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Main Authors: Omar Almaadawy, Mohamed Mar’ey Hesn, Yomna Ayman Elsalamony, Omar Ayman Abobakr, Abdelrahman Hossam Elshimy, Khaled Alsayed Abulkhair, Mahmoud Mohamed Negm, Ahmed Yasser Shaban, Yakubu Bene-Alhasan, Frank Annie, Adam Belcher, Ahmed Ramy Elashery
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:The Egyptian Heart Journal
Subjects:
siRNA
Lipoprotein(a)
Lp(a)
Inclisiran
Olpasiran
SLN360
Online Access:https://doi.org/10.1186/s43044-025-00635-1
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https://doi.org/10.1186/s43044-025-00635-1

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