The Barcelona baseline risk score to predict long-term prognosis after a first demyelinating event: a prospective observational studyResearch in context

The Barcelona baseline risk score to predict long-term prognosis after a first demyelinating event: a prospective observational studyResearch in context

Summary: Background: In multiple sclerosis (MS), predicting at symptom onset who will develop early and severe disability is an unmet need with significant therapeutic implications. Here we propose the Barcelona-Baseline Risk Score (BRS) model to predict long-term disease outcomes in a flexible and...

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Main Authors: Carmen Tur, Pere Carbonell-Mirabent, Susana Otero-Romero, Álvaro Cobo-Calvo, María Jesús Arévalo, Helena Ariño, Georgina Arrambide, Cristina Auger, René Carvajal, Joaquín Castilló, Manuel Comabella, Ingrid Galán, Luciana Midaglia, Carlos Nos, Agustín Pappolla, Deborah Pareto, Jordi Río, Breogán Rodríguez-Acevedo, Estibaliz Saez de Gordoa, Ángela Vidal-Jordana, Ana Zabalza, Jaume Sastre-Garriga, Àlex Rovira, Xavier Montalban, Mar Tintoré
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:The Lancet Regional Health. Europe
Subjects:
Multiple sclerosis
Predictive model
Disease progression
MRI
Progression independent of relapse activity
Relapse-associated worsening
Online Access:http://www.sciencedirect.com/science/article/pii/S2666776225000948
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