Evaluation of Bayesian Linear Regression derived gene set test methods

Evaluation of Bayesian Linear Regression derived gene set test methods

Abstract Background Gene set tests can pinpoint genes and biological pathways that exert small to moderate effects on complex diseases like Type 2 Diabetes (T2D). By aggregating genetic markers based on biological information, these tests can enhance the statistical power needed to detect genetic as...

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Bibliographic Details
Main Authors: Zhonghao Bai, Tahereh Gholipourshahraki, Merina Shrestha, Astrid Hjelholt, Sile Hu, Mads Kjolby, Palle Duun Rohde, Peter Sørensen
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Genomics
Subjects:
BLR
Type 2 diabetes
Complex disease
Gene set test
Online Access:https://doi.org/10.1186/s12864-024-11026-2
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https://doi.org/10.1186/s12864-024-11026-2

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