Assessment of TNF-α, IL-12/23, and IL-17 in Psoriasis: Only TNF-α Reflects Clinical Response After 12 Weeks of Biologic Treatment

Assessment of TNF-α, IL-12/23, and IL-17 in Psoriasis: Only TNF-α Reflects Clinical Response After 12 Weeks of Biologic Treatment

Background: Tumor necrosis factor-alpha (TNF-α), IL-12/23, IL-17A, and IL-17F are key proinflammatory cytokines involved in the pathogenesis of psoriasis. Biologic therapies targeting these interleukins have demonstrated clinical efficacy. However, the exact relationship between their serum levels a...

Full description

Saved in:
Bibliographic Details
Main Authors: Alessandra-Mădălina Matei-Man, Ștefan Cristian Vesa, Alexandra Dana Pușcaș, Meda Sandra Orăsan, Bianca Homorozeanu, Elisabeta Candrea, Teodora Mocan
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Current Issues in Molecular Biology
Subjects:
psoriasis
biomarkers
biologic therapy
TNF-α
Online Access:https://www.mdpi.com/1467-3045/47/5/368
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1467-3045/47/5/368

Similar Items