Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia

Biliary atresia is a rare idiopathic neonatal cholestatic disease characterized by the destruction of both the intra- and extrahepatic biliary ducts. As the disease is progressive all cases will develop portal fibrosis, cirrhosis, and portal hypertension with the sequelae of varices, jaundice, and e...

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Main Authors: O. E. O'Sullivan, D. Crosby, B. Byrne, C. Regan
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2013/421386
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author O. E. O'Sullivan
D. Crosby
B. Byrne
C. Regan
author_facet O. E. O'Sullivan
D. Crosby
B. Byrne
C. Regan
author_sort O. E. O'Sullivan
collection DOAJ
description Biliary atresia is a rare idiopathic neonatal cholestatic disease characterized by the destruction of both the intra- and extrahepatic biliary ducts. As the disease is progressive all cases will develop portal fibrosis, cirrhosis, and portal hypertension with the sequelae of varices, jaundice, and eventually liver failure requiring a transplant. Survival rates have improved considerably with many females living well in to be childbearing age. Due to the complexity of the disease these pregnancies are considered, high risk. We report the antenatal, intrapartum, and postpartum managements of a pregnancy complicated by biliary atresia. Furthermore, we highlight the importance of a multidisciplinary team approach in optimizing obstetric care for this high risk group.
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institution Kabale University
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publishDate 2013-01-01
publisher Wiley
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-4ca4a895c3854d97a600a2910d1fb96d2025-02-03T05:59:56ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922013-01-01201310.1155/2013/421386421386Pregnancy Complicated by Portal Hypertension Secondary to Biliary AtresiaO. E. O'Sullivan0D. Crosby1B. Byrne2C. Regan3Department of Fetomaternal Medicine, Coombe Women and Infants University Hospital, Dublin 8, IrelandDepartment of Fetomaternal Medicine, Coombe Women and Infants University Hospital, Dublin 8, IrelandDepartment of Fetomaternal Medicine, Coombe Women and Infants University Hospital, Dublin 8, IrelandDepartment of Fetomaternal Medicine, Coombe Women and Infants University Hospital, Dublin 8, IrelandBiliary atresia is a rare idiopathic neonatal cholestatic disease characterized by the destruction of both the intra- and extrahepatic biliary ducts. As the disease is progressive all cases will develop portal fibrosis, cirrhosis, and portal hypertension with the sequelae of varices, jaundice, and eventually liver failure requiring a transplant. Survival rates have improved considerably with many females living well in to be childbearing age. Due to the complexity of the disease these pregnancies are considered, high risk. We report the antenatal, intrapartum, and postpartum managements of a pregnancy complicated by biliary atresia. Furthermore, we highlight the importance of a multidisciplinary team approach in optimizing obstetric care for this high risk group.http://dx.doi.org/10.1155/2013/421386
spellingShingle O. E. O'Sullivan
D. Crosby
B. Byrne
C. Regan
Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia
Case Reports in Obstetrics and Gynecology
title Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia
title_full Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia
title_fullStr Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia
title_full_unstemmed Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia
title_short Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia
title_sort pregnancy complicated by portal hypertension secondary to biliary atresia
url http://dx.doi.org/10.1155/2013/421386
work_keys_str_mv AT oeosullivan pregnancycomplicatedbyportalhypertensionsecondarytobiliaryatresia
AT dcrosby pregnancycomplicatedbyportalhypertensionsecondarytobiliaryatresia
AT bbyrne pregnancycomplicatedbyportalhypertensionsecondarytobiliaryatresia
AT cregan pregnancycomplicatedbyportalhypertensionsecondarytobiliaryatresia