Characteristics and outcomes of patients with double refractory and double exposed chronic lymphocytic leukemia

Characteristics and outcomes of patients with double refractory and double exposed chronic lymphocytic leukemia

Abstract: We analyzed the characteristics and outcomes of 95 patients with chronic lymphocytic leukemia (CLL) after Bruton tyrosine kinase inhibitor (BTKi) and B-cell lymphoma 2 inhibitor (BCL2i) failure. To clearly distinguish sensitivity and resistance to the targeted treatment classes, we defined...

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Main Authors: James T. Yoon, Yinglu Zhou, Mariia Mikhaleva, Daniel S. Choi, Stacey M. Fernandes, Philippe Armand, Amy C. Bessnow, Jennifer L. Crombie, David C. Fisher, Eric D. Jacobsen, Caron A. Jacobson, Austin I. Kim, Ann S. LaCasce, Reid W. Merryman, Oreofe O. Odejide, Erin M. Parry, David A. Qualls, Christine E. Ryan, Aswin Sekar, Jacob D. Soumerai, Jon Arnason, Svitlana Tyekucheva, Matthew S. Davids, Jennifer R. Brown, Inhye E. Ahn
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925001958
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