Optimization of Inspired Oxygen during Mechanical Ventilation (OPTI-OXYGEN): rationale and design of a pragmatic randomised controlled trial

Introduction Targeted oxygenation protocols in mechanically ventilated patients are critical in avoiding the deleterious effects of hypoxaemia and hyperoxaemia. Peripheral oxygen saturation (SpO2) is a practical metric that commonly drives oxygen titration protocols and guidelines but has inaccuraci...

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Bibliographic Details
Main Authors: Taylor B Thompson, Todd W Rice, Guy N Brock, Jonathan Peters, Elliott D Crouser, Matthew Exline, Sonal R Pannu, Jamie Zimmer, Jeffrey C Horowitz
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/6/e094924.full
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