Fatty acids promote migration of CD4+ T cells through calcium release-activated calcium modulator ORAI1 sensitive glycolysis in dairy cows

Fatty acids promote migration of CD4+ T cells through calcium release-activated calcium modulator ORAI1 sensitive glycolysis in dairy cows

ABSTRACT: Nutritional and metabolic state in dairy cows are important determinants of the immune response. During the periparturient period, a state of negative energy balance in the cow increases plasma concentrations of fatty acids (FA), which are associated with inflammation. Among immune cells,...

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Bibliographic Details
Main Authors: Bingbing Zhang, Jianan Wen, Ming Li, Jingjing Wang, Ziwei Ji, Xinquan Lv, Muhammad Usman, John Mauck, Juan J. Loor, Wei Yang, Guihua Wang, Jinzhu Ma, Chuang Xu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Dairy Science
Subjects:
high FA
CD4+ T cells
glycolysis
SOCE
migration
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030224012438
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