Detection of 11q23 (MLL) rearrangements in infant acute lymphoblastic leukemia

Detection of 11q23 (MLL) rearrangements in infant acute lymphoblastic leukemia

117 cases of infant acute lymphoblastic leukemia without Down syndrome (aged from 1 to 365 days) were included in the current study.Rearrangements of 11q23 (MLL) were revealed in 74 (63.2 %) patients. Among this group the most common rearrangement was t(4;11) q21;q23)/MLL-AF4 detected in 63.5 % case...

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Main Authors: G. A. Tsaur, A. M. Popov, O. V. Aleynikova, E. G. Boychenko, T. Yu. Verzhbitskaya, E. V. Volochnik, A. S. Ivanova, O. V. Kalennik, S. Yu. Kovalev, K. L. Kondtratchik, A. M. Kustanovich, E. S. Lapotentova, D. V. Litvinov, I. S. Martynkevich, N. V. Myakova, T. V. Nasedkina, V. A. Ovsepyan, Yu. V. Olshanskaya, O. M. Plehanova, A. V. Popa, T. O. Riger, L. I. Savelyev, O. V. Streneva, M. V. Strigaleva, I. V. Shmunk, E. V. Shorikov, L. G. Fechina
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Онкогематология
Subjects:
acute lymphoblastic leukemia
infants
translocation 11q23
mll rearrangements
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/91
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https://oncohematology.abvpress.ru/ongm/article/view/91

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