Interpretability-guided RNA N6-methyladenosine modification site prediction with invertible neural networks

Abstract As one of the most common and abundant post-transcriptional modifications, N6-methyladenosine (m6A) has been extensively studied for its essential regulatory role in gene expression and cell functions. The location of m6A RNA modification sites, however, remains a challenging problem, becau...

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Bibliographic Details
Main Authors: Guodong Li, Xiaorui Su, Yue Yang, Dongxu Li, Ziwen Cui, Xun Deng, Pengwei Hu, Lun Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08265-8
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