Murine DX5+NKT Cells Display Their Cytotoxic and Proapoptotic Potentials against Colitis-Inducing CD4+CD62Lhigh T Cells through Fas Ligand
Introduction. It has been previously shown that immunoregulatory DX5+NKT cells are able to prevent colitis induced by CD4+CD62Lhigh T lymphocytes in a SCID mouse model. The aim of this study was to further investigate the underlying mechanism in vitro. Methods. CD4+CD62Lhigh and DX5+NKT cells from t...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2018/8175810 |
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