Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency?
Iodine deficiency during pregnancy can cause iodine deficiency disorders (IDD). However, it is unclear about iodine and thyroid status of Chinese pregnant women and neonates after the implementation of the revised universal salt iodisation (USI) level in 2012. Therefore, the aim of the cross-section...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2019/3618169 |
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| author | Hang Zhou Zheng Feei Ma Yiming Lu Binyu Pan Jian Shao Liya Wang Yanyan Du Qihua Zhao |
| author_facet | Hang Zhou Zheng Feei Ma Yiming Lu Binyu Pan Jian Shao Liya Wang Yanyan Du Qihua Zhao |
| author_sort | Hang Zhou |
| collection | DOAJ |
| description | Iodine deficiency during pregnancy can cause iodine deficiency disorders (IDD). However, it is unclear about iodine and thyroid status of Chinese pregnant women and neonates after the implementation of the revised universal salt iodisation (USI) level in 2012. Therefore, the aim of the cross-sectional study was to determine iodine nutrition and thyroid status among pregnant women and their neonates in China after the implementation of USI. Medical records of pregnant women and neonates in Northern Jiangsu People’s Hospital between January 2016 and December 2017 were reviewed and included. We included 3060 mother-and-newborn pairs in the study. Mean age of participants was 28.2 ± 4.1 years. TSH, FT3, and FT4 of participants were within normal reference range. The overall mean neonatal TSH, birth weight, and prevalence of low birth weight (LBW) were 4.86 ± 2.06 mIU/L, 3358 ± 455 g, and 3.2%, respectively. The prevalence of neonatal TSH values >5 mIU/L was 29.3%, suggesting iodine deficiency in the region. In conclusion, our results indicated iodine deficiency in the region, according to the neonatal TSH cutoff recommended by WHO/UNICEF/IGD. More efforts are urgently required to improve iodine status of pregnant women in the region in order to prevent a re-emergence of iodine deficiency. |
| format | Article |
| id | doaj-art-4b99c723a73544a5b9c31319013ca05b |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-4b99c723a73544a5b9c31319013ca05b2025-02-03T01:23:21ZengWileyInternational Journal of Endocrinology1687-83371687-83452019-01-01201910.1155/2019/36181693618169Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency?Hang Zhou0Zheng Feei Ma1Yiming Lu2Binyu Pan3Jian Shao4Liya Wang5Yanyan Du6Qihua Zhao7Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, ChinaDepartment of Health and Environmental Sciences, Xi’an Jiaotong-Liverpool University, Suzhou 215123, Jiangsu Province, ChinaClinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, ChinaDepartment of Clinical Nutrition, The First People’s Hospital of Wujiang District, Suzhou 215200, Jiangsu Province, ChinaClinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, ChinaClinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, ChinaClinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, ChinaClinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, ChinaIodine deficiency during pregnancy can cause iodine deficiency disorders (IDD). However, it is unclear about iodine and thyroid status of Chinese pregnant women and neonates after the implementation of the revised universal salt iodisation (USI) level in 2012. Therefore, the aim of the cross-sectional study was to determine iodine nutrition and thyroid status among pregnant women and their neonates in China after the implementation of USI. Medical records of pregnant women and neonates in Northern Jiangsu People’s Hospital between January 2016 and December 2017 were reviewed and included. We included 3060 mother-and-newborn pairs in the study. Mean age of participants was 28.2 ± 4.1 years. TSH, FT3, and FT4 of participants were within normal reference range. The overall mean neonatal TSH, birth weight, and prevalence of low birth weight (LBW) were 4.86 ± 2.06 mIU/L, 3358 ± 455 g, and 3.2%, respectively. The prevalence of neonatal TSH values >5 mIU/L was 29.3%, suggesting iodine deficiency in the region. In conclusion, our results indicated iodine deficiency in the region, according to the neonatal TSH cutoff recommended by WHO/UNICEF/IGD. More efforts are urgently required to improve iodine status of pregnant women in the region in order to prevent a re-emergence of iodine deficiency.http://dx.doi.org/10.1155/2019/3618169 |
| spellingShingle | Hang Zhou Zheng Feei Ma Yiming Lu Binyu Pan Jian Shao Liya Wang Yanyan Du Qihua Zhao Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency? International Journal of Endocrinology |
| title | Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency? |
| title_full | Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency? |
| title_fullStr | Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency? |
| title_full_unstemmed | Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency? |
| title_short | Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency? |
| title_sort | assessment of iodine status among pregnant women and neonates using neonatal thyrotropin tsh in mainland china after the introduction of new revised universal salt iodisation usi in 2012 a re emergence of iodine deficiency |
| url | http://dx.doi.org/10.1155/2019/3618169 |
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