Q221K mutation in VP2 drives antigenic shift of infectious bursal disease virus

Q221K mutation in VP2 drives antigenic shift of infectious bursal disease virus

IntroductionInfectious bursal disease (IBD) is a severe immunosuppressive disease caused by the infection of infectious bursal disease virus (IBDV) in chicken. Recently, an emerging mutant named novel variant IBDV (nVarIBDV) has rapidly spread in China and become a prevalent strain. However, little...

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Bibliographic Details
Main Authors: Haifeng Xiong, Jiayan Wu, Quan Xie, Tuofan Li, Zhimin Wan, Aijian Qin, Jianqiang Ye, Hongxia Shao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
nVarIBDV
VP2
mAb
221K
antigenicity
differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1600371/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1600371/full

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