Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses

Simian immunodeficiency viruses (SIVs) comprise a large group of primate lentiviruses that endemically infect African monkeys. HIV-1 spilled over to humans from this viral reservoir, but the spillover did not occur directly from monkeys to humans. Instead, a key event was the introduction of SIVs in...

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Bibliographic Details
Main Authors: Cody J Warren, Arturo Barbachano-Guerrero, Vanessa L Bauer, Alex Stabell, Obaiah Dirasantha, Qing Yang, Sara L Sawyer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
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Online Access:https://elifesciences.org/articles/93316
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