Matrix rigidity regulates cancer cell growth and cellular phenotype.

Matrix rigidity regulates cancer cell growth and cellular phenotype.

<h4>Background</h4>The mechanical properties of the extracellular matrix have an important role in cell growth and differentiation. However, it is unclear as to what extent cancer cells respond to changes in the mechanical properties (rigidity/stiffness) of the microenvironment and how t...

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Bibliographic Details
Main Authors: Robert W Tilghman, Catharine R Cowan, Justin D Mih, Yulia Koryakina, Daniel Gioeli, Jill K Slack-Davis, Brett R Blackman, Daniel J Tschumperlin, J Thomas Parsons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012905&type=printable
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