Dehydrothyrsiferol Against Cutaneous Leishmaniasis: Treatment Outcome in a Murine Model

Dehydrothyrsiferol Against Cutaneous Leishmaniasis: Treatment Outcome in a Murine Model

One of the most important steps in preclinical drug discovery is to demonstrate the in vivo efficacy of potential leishmanicidal compounds and good characteristics at the level of parasite killing prior to initiating human clinical trials. This paper describes the use of dehydrothyrsiferol (DT), iso...

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Main Authors: Atteneri López-Arencibia, Carlos J. Bethencourt-Estrella, Desirée San Nicolás-Hernández, Rubén L. Rodríguez-Expósito, Angélica Domínguez-de-Barros, Lizbeth Salazar-Villatoro, Maritza Omaña-Molina, Francisco Cen-Pacheco, Ana R. Díaz-Marrero, José J. Fernández, Elizabeth Córdoba-Lanús, Jacob Lorenzo-Morales, José E. Piñero
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Marine Drugs
Subjects:
dehydrothyrsiferol
marine oxasqualenoid
<i>Leishmania amazonensis</i>
cutaneous leishmaniasis
Online Access:https://www.mdpi.com/1660-3397/23/1/13
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