Toll-like receptor-mediated immune imbalance in asthma: controversies, breakthroughs, and future directions

As a chronic inflammatory illness of the respiratory system, asthma occurs due to various factors and is characterized by a T helper 2 (Th2)-skewed immune response, airway hyperresponsiveness, and reversible airflow obstruction. Toll-like receptors (TLRs) perform a “double-edged sword” function in a...

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Bibliographic Details
Main Authors: Xinyi Xu, Ruihan Yu, Zhuoqun Yang, Chenyu Li, Huabao Xiong, Chunxia Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1605185/full
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