Downregulation of tropomyosin 2 promotes the progression of lung adenocarcinoma by regulating neutrophil infiltration through neutrophil elastase

Abstract Lung adenocarcinoma (LUAD) is a common malignant tumor in the lung that seriously endangers the health of people worldwide. The neutrophil-associated inflammatory microenvironment contributes to the activation of tumor cells. In this study, we report a role of tumor-associated neutrophils (...

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Bibliographic Details
Main Authors: Caixiu Huang, Hao Qiu, Changting Xu, Zilong Tan, Mei Jin, Jing Hu, Zhilong Huang, Yuwei Zhou, Shengyou Ge, Xiaoyuan Hu
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07531-1
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