Association studies of calcium-sensing receptor (CaSR) polymorphisms with serum concentrations of glucose and phosphate, and vascular calcification in renal transplant recipients.

Association studies of calcium-sensing receptor (CaSR) polymorphisms with serum concentrations of glucose and phosphate, and vascular calcification in renal transplant recipients.

<h4>Background</h4>Cardiovascular disease is the major cause of death in renal transplant recipients (RTRs) and linked to arterial calcification. The calcium-sensing receptor (CaSR), a G-protein coupled receptor, plays a pivotal role in extracellular calcium homeostasis and is expressed...

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Main Authors: Valerie N Babinsky, Fadil M Hannan, Sonia C Youhanna, Céline Maréchal, Michel Jadoul, Olivier Devuyst, Rajesh V Thakker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0119459&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0119459&type=printable

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