Sox2-overexpressing neural stem cells alleviate ventricular enlargement and neurological dysfunction in posthemorrhagic hydrocephalus

Sox2-overexpressing neural stem cells alleviate ventricular enlargement and neurological dysfunction in posthemorrhagic hydrocephalus

Neural stem cells (NSCs) have the potential for self-renewal and multidirectional differentiation, and their transplantation has achieved good efficacy in a variety of diseases. However, only 1%–10% of transplanted NSCs survive in the ischemic and hypoxic microenvironment of posthemorrhagic hydrocep...

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Bibliographic Details
Main Authors: Baocheng Gao, Haoxiang Wang, Shuang Hu, Kunhong Zhong, Xiaoyin Liu, Ziang Deng, Yuanyou Li, Aiping Tong, Liangxue Zhou
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-02-01
Series:Neural Regeneration Research
Subjects:
angiogenesis
cerebrospinal fluid
hippocampal transplantation
inflammation
microglia
neural stem cells
neurogenesis
posthemorrhagic hydrocephalus
retinoic acid
sox2
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-01491
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https://journals.lww.com/10.4103/NRR.NRR-D-24-01491

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