Regulation of inflammatory cytokines and activation of PI3K/Akt pathway by Yiqi Jiedu Formula in recurrent Herpes Simplex Keratitis: Experimental and network pharmacology evidence

Regulation of inflammatory cytokines and activation of PI3K/Akt pathway by Yiqi Jiedu Formula in recurrent Herpes Simplex Keratitis: Experimental and network pharmacology evidence

Objective: This study investigates the therapeutic effects of the Yiqi Jiedu (YQJD) formula on Herpes Simplex Keratitis (HSK) induced by herpes simplex virus type 1 (HSV-1) and elucidates its mechanisms of action through experimental and network pharmacology approaches. Methods: Active ingredients o...

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Bibliographic Details
Main Authors: Shuyu Xiao, Wanhong Miao, Leilei Wang, Lei Wang, Sisi Tang, Huihui Xu, Ying Yu
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Virus Research
Subjects:
Herpes Simplex Keratitis
Network pharmacology
Molecular docking
Akt signaling pathway
Interleukin-4
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170225000383
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