Genetic evidence for the causal effect of clonal hematopoiesis on pulmonary arterial hypertension

Genetic evidence for the causal effect of clonal hematopoiesis on pulmonary arterial hypertension

Abstract Background Pulmonary arterial hypertension (PAH) is a severe and progressive cardiovascular disease. While potential links between clonal hematopoiesis (CH) and cardiovascular diseases have been identified, the causal relationship between CH and PAH remains unclear. This study aims to inves...

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Bibliographic Details
Main Authors: Jia-Yong Qiu, Shen-Shen Huang, Chao Liu, Dong Ding, Yan-Hong Xu, Yi-Min Mao, Ya-Dong Yuan
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cardiovascular Disorders
Subjects:
Pulmonary arterial hypertension
Clonal hematopoiesis
Mendelian randomization
TET2
Inflammation
Online Access:https://doi.org/10.1186/s12872-025-04475-4
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