Repeated sevoflurane exposure causes hypomyelination in the prefrontal cortex of adult male mice

Abstract As one of the most commonly used general anesthetics (GAs) in surgery, numerous studies have demonstrated the detrimental effects of sevoflurane exposure on myelination in the developing and elderly brain. However, the impact of sevoflurane exposure on intact myelin structure in the adult b...

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Bibliographic Details
Main Authors: Linyong Zhang, Zhidan Ke, Ning Zhang, Dechuan Wang, Liang Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85834-1
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