Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children

Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children

ABSTRACT T follicular helper (Tfh) cells are crucial for B cell activation and subsequent antibody production. This functionality is influenced by surface markers such as CD40L, a costimulatory factor which promotes B cell activation, and CD57, which is a well-known marker of senescence. This study...

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Bibliographic Details
Main Authors: Dana M. Van Fossen, Hyunjae Cho, Lisa E. Wagar, Jennie Z. Ma, Julie Parsonnet, Rashidul Haque, Mark M. Davis, William A. Petri
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:mBio
Subjects:
T follicular helper cells
immune dysfunction
malnutrition
childhood immunity
antibiotic exposure
T cell exhaustion
Online Access:https://journals.asm.org/doi/10.1128/mbio.03980-24
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https://journals.asm.org/doi/10.1128/mbio.03980-24

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