Neoadjuvant toripalimab combined with axitinib in patients with locally advanced clear cell renal cell carcinoma: a single-arm, phase II trial

Neoadjuvant toripalimab combined with axitinib in patients with locally advanced clear cell renal cell carcinoma: a single-arm, phase II trial

Background A combination of axitinib and immune checkpoint inhibitors (ICIs) demonstrated promising efficacy in the treatment of advanced renal cell carcinoma (RCC). This study aims to prospectively evaluate the safety, efficacy, and biomarkers of neoadjuvant toripalimab plus axitinib in non-metasta...

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Main Authors: Wei Zhang, Ding Zhang, Fan Xu, Wei Xue, Jin Zhang, Xiaorong Wu, Guangyu Wu, Jiwei Huang, Yueming Wang, Zaoyu Wang, Wen Kong, NG Cheoklong, Thibault Tricard, Wei Zhai, Jiyang Zhang, Shuyin Chen, Yuqing Lian, Yonghui Chen, Yiran Huang
Format: Article
Language:English
Published: BMJ Publishing Group 2024-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/6/e008475.full
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https://jitc.bmj.com/content/12/6/e008475.full

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