An evolutionary perspective on epistasis and the missing heritability.

The relative importance between additive and non-additive genetic variance has been widely argued in quantitative genetics. By approaching this question from an evolutionary perspective we show that, while additive variance can be maintained under selection at a low level for some patterns of epista...

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Bibliographic Details
Main Authors: Gibran Hemani, Sara Knott, Chris Haley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-02-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003295&type=printable
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