Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.

Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.

Tuberculosis (TB) remains a leading cause of mortality worldwide. With the emergence of multidrug resistant TB, extensively drug resistant TB and HIV-associated TB it is imperative that new drug targets be identified. The potential of Mycobacterium tuberculosis inosine monophosphate dehydrogenase (I...

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Bibliographic Details
Main Authors: Veeraraghavan Usha, Judith V Hobrath, Sudagar S Gurcha, Robert C Reynolds, Gurdyal S Besra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0033886&type=printable
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