Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control study
BackgroundElectroconvulsive therapy (ECT)-induced fever can significantly affect patient experience, treatment adherence, and the course of treatment. However, little is known about the prevalence of ECT-induced fever and its associated risk factors in patients with major mental disorders (MMD).Meth...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1530533/full |
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| author | Can-Jin Deng Can-Jin Deng Jian-Wen Yang Jian-Wen Yang Zi-Zhe Liu Zi-Zhe Liu Ting Ning Ting Ning Sha Nie Sha Nie Xiong Huang Xiong Huang Xin-Hu Yang Xin-Hu Yang Xing-Bing Huang Xing-Bing Huang Wei Zheng Wei Zheng |
| author_facet | Can-Jin Deng Can-Jin Deng Jian-Wen Yang Jian-Wen Yang Zi-Zhe Liu Zi-Zhe Liu Ting Ning Ting Ning Sha Nie Sha Nie Xiong Huang Xiong Huang Xin-Hu Yang Xin-Hu Yang Xing-Bing Huang Xing-Bing Huang Wei Zheng Wei Zheng |
| author_sort | Can-Jin Deng |
| collection | DOAJ |
| description | BackgroundElectroconvulsive therapy (ECT)-induced fever can significantly affect patient experience, treatment adherence, and the course of treatment. However, little is known about the prevalence of ECT-induced fever and its associated risk factors in patients with major mental disorders (MMD).MethodsThis retrospective, case-control study included 113 cases and 226 age-matched controls (1:2). The case group comprised patients who exhibited an axillary temperature of ≥37.5°C (99.5°F) at least once within 24 hours post-ECT. Patients diagnosed with MMD underwent ECT between January 1, 2021, and December 31, 2021, at a large psychiatric hospital in China. Demographic and clinical data were extracted from the electronic chart management system (ECMS) for both groups.ResultsThe prevalence of ECT-induced fever in patients with MMD was 6.8% [113/1,674, 95% confidence interval (CI): 5.6% to 8.0%], with a session-based prevalence of 1.1% (130/11,570, 95% CI: 0.9% to 1.3%). Multivariate logistic regression analysis identified paliperidone [odds ratios (OR)=2.5, 95% CI: 1.2 to 4.9] as a risk factor, while quetiapine (OR=0.4, 95% CI: 0.3 to 0.8) was found to be protective. No significant association between etomidate and ECT-induced fever was observed in univariate analysis (p>0.05).ConclusionsThis study found a relatively low prevalence of ECT-induced fever. Paliperidone was identified as a risk factor, while quetiapine had a protective effect. Etomidate was not significantly associated with ECT-induced fever in patients with MMD. |
| format | Article |
| id | doaj-art-48a34ecdaee448de8209042074b4c34a |
| institution | Kabale University |
| issn | 1664-0640 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Psychiatry |
| spelling | doaj-art-48a34ecdaee448de8209042074b4c34a2025-01-24T07:13:50ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-01-011510.3389/fpsyt.2024.15305331530533Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control studyCan-Jin Deng0Can-Jin Deng1Jian-Wen Yang2Jian-Wen Yang3Zi-Zhe Liu4Zi-Zhe Liu5Ting Ning6Ting Ning7Sha Nie8Sha Nie9Xiong Huang10Xiong Huang11Xin-Hu Yang12Xin-Hu Yang13Xing-Bing Huang14Xing-Bing Huang15Wei Zheng16Wei Zheng17Psychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaPsychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaPsychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaPsychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaPsychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaPsychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaPsychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaPsychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaPsychiatry Department, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, ChinaBackgroundElectroconvulsive therapy (ECT)-induced fever can significantly affect patient experience, treatment adherence, and the course of treatment. However, little is known about the prevalence of ECT-induced fever and its associated risk factors in patients with major mental disorders (MMD).MethodsThis retrospective, case-control study included 113 cases and 226 age-matched controls (1:2). The case group comprised patients who exhibited an axillary temperature of ≥37.5°C (99.5°F) at least once within 24 hours post-ECT. Patients diagnosed with MMD underwent ECT between January 1, 2021, and December 31, 2021, at a large psychiatric hospital in China. Demographic and clinical data were extracted from the electronic chart management system (ECMS) for both groups.ResultsThe prevalence of ECT-induced fever in patients with MMD was 6.8% [113/1,674, 95% confidence interval (CI): 5.6% to 8.0%], with a session-based prevalence of 1.1% (130/11,570, 95% CI: 0.9% to 1.3%). Multivariate logistic regression analysis identified paliperidone [odds ratios (OR)=2.5, 95% CI: 1.2 to 4.9] as a risk factor, while quetiapine (OR=0.4, 95% CI: 0.3 to 0.8) was found to be protective. No significant association between etomidate and ECT-induced fever was observed in univariate analysis (p>0.05).ConclusionsThis study found a relatively low prevalence of ECT-induced fever. Paliperidone was identified as a risk factor, while quetiapine had a protective effect. Etomidate was not significantly associated with ECT-induced fever in patients with MMD.https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1530533/fullelectroconvulsive therapy-induced feverelectroconvulsive therapyrisk factorsprevalenceadverse effects |
| spellingShingle | Can-Jin Deng Can-Jin Deng Jian-Wen Yang Jian-Wen Yang Zi-Zhe Liu Zi-Zhe Liu Ting Ning Ting Ning Sha Nie Sha Nie Xiong Huang Xiong Huang Xin-Hu Yang Xin-Hu Yang Xing-Bing Huang Xing-Bing Huang Wei Zheng Wei Zheng Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control study Frontiers in Psychiatry electroconvulsive therapy-induced fever electroconvulsive therapy risk factors prevalence adverse effects |
| title | Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control study |
| title_full | Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control study |
| title_fullStr | Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control study |
| title_full_unstemmed | Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control study |
| title_short | Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control study |
| title_sort | risk factors for electroconvulsive therapy induced fever a retrospective case control study |
| topic | electroconvulsive therapy-induced fever electroconvulsive therapy risk factors prevalence adverse effects |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1530533/full |
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