Combining time domain modulation optofluidics and high dynamic range imaging for multiplexed, high throughput digital droplet assays

Abstract Digital enzyme-linked immunoassays (dELISA) have been successfully applied to the ultrasensitive quantification of analytes, including nucleic acids, proteins, cells, and extracellular vesicles, achieving robust detection limits in complex clinical specimens such as blood, and demonstrating...

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Bibliographic Details
Main Authors: Yasemin Atiyas, Michael J. Siedlik, Stephanie J. Yang, David A. Issadore
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-025-00918-2
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