Biochemical mapping reveals a conserved heme transport mechanism via CcmCD in System I bacterial cytochrome c biogenesis

ABSTRACT Heme is a redox-active cofactor for essential processes across all domains of life. Heme’s redox capabilities are responsible for its biological significance but also make it highly cytotoxic, requiring tight intracellular regulation. Thus, the mechanisms of heme trafficking are still not w...

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Bibliographic Details
Main Authors: Alicia N. Kreiman, Sarah E. Garner, Susan C. Carroll, Molly C. Sutherland
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.03515-24
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