Recurrent Multifocal Mycoplasma orale Infection in an Immunocompromised Patient: A Case Report and Review

A young woman with mixed connective tissue disease complicated by erosive arthritis, secondary hypogammaglobulinemia due to rituximab, and a history of many infectious complications developed multiple nonhealing wounds, polyarticular joint pain, and leukocytosis. Radiographic studies demonstrated mu...

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Main Authors: Jeffrey Ketchersid, Jake Scott, Thomas Lew, Niaz Banaei, Shanthi Kappagoda
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2020/8852115
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author Jeffrey Ketchersid
Jake Scott
Thomas Lew
Niaz Banaei
Shanthi Kappagoda
author_facet Jeffrey Ketchersid
Jake Scott
Thomas Lew
Niaz Banaei
Shanthi Kappagoda
author_sort Jeffrey Ketchersid
collection DOAJ
description A young woman with mixed connective tissue disease complicated by erosive arthritis, secondary hypogammaglobulinemia due to rituximab, and a history of many infectious complications developed multiple nonhealing wounds, polyarticular joint pain, and leukocytosis. Radiographic studies demonstrated multiple scattered areas of osteomyelitis and complex abscesses. Purulent fluid drained from multiple sites did not yield a microbiologic diagnosis by standard culture technique, but Mycoplasma orale was ultimately identified using 16 S ribosomal RNA gene amplification and sequencing. We describe this unique case and review the literature.
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institution Kabale University
issn 2090-6625
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language English
publishDate 2020-01-01
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record_format Article
series Case Reports in Infectious Diseases
spelling doaj-art-481ef4f75da14fb9a2f5a7b159a5043a2025-02-03T01:04:48ZengWileyCase Reports in Infectious Diseases2090-66252090-66332020-01-01202010.1155/2020/88521158852115Recurrent Multifocal Mycoplasma orale Infection in an Immunocompromised Patient: A Case Report and ReviewJeffrey Ketchersid0Jake Scott1Thomas Lew2Niaz Banaei3Shanthi Kappagoda4Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USADepartment of Medicine–Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Palo Alto, CA, USADepartment of Medicine, Stanford University School of Medicine, Palo Alto, CA, USADepartment of Medicine–Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Palo Alto, CA, USADepartment of Medicine–Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Palo Alto, CA, USAA young woman with mixed connective tissue disease complicated by erosive arthritis, secondary hypogammaglobulinemia due to rituximab, and a history of many infectious complications developed multiple nonhealing wounds, polyarticular joint pain, and leukocytosis. Radiographic studies demonstrated multiple scattered areas of osteomyelitis and complex abscesses. Purulent fluid drained from multiple sites did not yield a microbiologic diagnosis by standard culture technique, but Mycoplasma orale was ultimately identified using 16 S ribosomal RNA gene amplification and sequencing. We describe this unique case and review the literature.http://dx.doi.org/10.1155/2020/8852115
spellingShingle Jeffrey Ketchersid
Jake Scott
Thomas Lew
Niaz Banaei
Shanthi Kappagoda
Recurrent Multifocal Mycoplasma orale Infection in an Immunocompromised Patient: A Case Report and Review
Case Reports in Infectious Diseases
title Recurrent Multifocal Mycoplasma orale Infection in an Immunocompromised Patient: A Case Report and Review
title_full Recurrent Multifocal Mycoplasma orale Infection in an Immunocompromised Patient: A Case Report and Review
title_fullStr Recurrent Multifocal Mycoplasma orale Infection in an Immunocompromised Patient: A Case Report and Review
title_full_unstemmed Recurrent Multifocal Mycoplasma orale Infection in an Immunocompromised Patient: A Case Report and Review
title_short Recurrent Multifocal Mycoplasma orale Infection in an Immunocompromised Patient: A Case Report and Review
title_sort recurrent multifocal mycoplasma orale infection in an immunocompromised patient a case report and review
url http://dx.doi.org/10.1155/2020/8852115
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