Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of Testing
Harmane, a potent neurotoxin linked with several neurological disorders, is present in many foods, coffee, and cigarettes. We assessed whether morning food/coffee consumption and smoking were reflected in blood harmane concentrations (BHCs) we obtained in an epidemiologic sample (𝑛=497). Participant...
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| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/2011/628151 |
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| author | Elan D. Louis Pam Factor-Litvak Marina Gerbin Wendy Jiang Wei Zheng |
| author_facet | Elan D. Louis Pam Factor-Litvak Marina Gerbin Wendy Jiang Wei Zheng |
| author_sort | Elan D. Louis |
| collection | DOAJ |
| description | Harmane, a potent neurotoxin linked with several neurological disorders, is present in many foods, coffee, and cigarettes. We assessed whether morning food/coffee consumption and smoking were reflected in blood harmane concentrations (BHCs) we obtained in an epidemiologic sample (𝑛=497). Participants who smoked on the morning of phlebotomy had similar logBHCs to those who had not smoked (𝑃=.57); there was no correlation between logBHCs and number of cigarettes (𝑃=.59). Among the coffee drinkers, there was no correlation between number of cups and logBHCs (𝑃=.98). Participants who had eaten on the morning of phlebotomy had similar logBHCs to those who had not (𝑃=.49); logBHCs did not correlate with the time latency between last food consumption and phlebotomy (𝑃=.74). BHCs in this sample of ~500 individuals did not covary with recent smoking, coffee, or food consumption, suggesting that our inability to withhold these exposures on the morning of phlebotomy was not reflected in the BHCs we measured. |
| format | Article |
| id | doaj-art-4803b21dcfc64b93be3f23e4a4d2d417 |
| institution | Kabale University |
| issn | 1687-8191 1687-8205 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Toxicology |
| spelling | doaj-art-4803b21dcfc64b93be3f23e4a4d2d4172025-02-03T01:03:18ZengWileyJournal of Toxicology1687-81911687-82052011-01-01201110.1155/2011/628151628151Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of TestingElan D. Louis0Pam Factor-Litvak1Marina Gerbin2Wendy Jiang3Wei Zheng4GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, Unit 198, Neurological Institute, 710 West 168th Street, New York, NY 10032-2699, USADepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032-3727, USAGH Sergievsky Center, College of Physicians and Surgeons, Columbia University, Unit 198, Neurological Institute, 710 West 168th Street, New York, NY 10032-2699, USASchool of Health Sciences, Purdue University, West Lafayette, IN 47907-2051, USASchool of Health Sciences, Purdue University, West Lafayette, IN 47907-2051, USAHarmane, a potent neurotoxin linked with several neurological disorders, is present in many foods, coffee, and cigarettes. We assessed whether morning food/coffee consumption and smoking were reflected in blood harmane concentrations (BHCs) we obtained in an epidemiologic sample (𝑛=497). Participants who smoked on the morning of phlebotomy had similar logBHCs to those who had not smoked (𝑃=.57); there was no correlation between logBHCs and number of cigarettes (𝑃=.59). Among the coffee drinkers, there was no correlation between number of cups and logBHCs (𝑃=.98). Participants who had eaten on the morning of phlebotomy had similar logBHCs to those who had not (𝑃=.49); logBHCs did not correlate with the time latency between last food consumption and phlebotomy (𝑃=.74). BHCs in this sample of ~500 individuals did not covary with recent smoking, coffee, or food consumption, suggesting that our inability to withhold these exposures on the morning of phlebotomy was not reflected in the BHCs we measured.http://dx.doi.org/10.1155/2011/628151 |
| spellingShingle | Elan D. Louis Pam Factor-Litvak Marina Gerbin Wendy Jiang Wei Zheng Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of Testing Journal of Toxicology |
| title | Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of Testing |
| title_full | Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of Testing |
| title_fullStr | Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of Testing |
| title_full_unstemmed | Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of Testing |
| title_short | Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of Testing |
| title_sort | blood harmane concentrations in 497 individuals relative to coffee cigarettes and food consumption on the morning of testing |
| url | http://dx.doi.org/10.1155/2011/628151 |
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