Therapeutic implications for the PD-1 axis in cerebrovascular injury
Since the discovery and characterization of the PD-1/PD-L pathway, mounting evidence has emerged regarding its role in regulating neuroinflammation following cerebrovascular injury. Classically, PD-L1 on antigen-presenting cells or tissues binds PD-1 on T cell surfaces resulting in T cell inhibition...
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Main Authors: | James Feghali, Christopher M. Jackson |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Neurotherapeutics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878747924001466 |
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