Therapeutic implications for the PD-1 axis in cerebrovascular injury

Since the discovery and characterization of the PD-1/PD-L pathway, mounting evidence has emerged regarding its role in regulating neuroinflammation following cerebrovascular injury. Classically, PD-L1 on antigen-presenting cells or tissues binds PD-1 on T cell surfaces resulting in T cell inhibition...

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Bibliographic Details
Main Authors: James Feghali, Christopher M. Jackson
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Neurotherapeutics
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Online Access:http://www.sciencedirect.com/science/article/pii/S1878747924001466
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