Live attenuated S. Typhimurium vaccine with improved safety in immuno-compromised mice.

Live attenuated vaccines are of great value for preventing infectious diseases. They represent a delicate compromise between sufficient colonization-mediated adaptive immunity and minimizing the risk for infection by the vaccine strain itself. Immune defects can predispose to vaccine strain infectio...

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Bibliographic Details
Main Authors: Balamurugan Periaswamy, Lisa Maier, Vikalp Vishwakarma, Emma Slack, Marcus Kremer, Helene L Andrews-Polymenis, Michael McClelland, Andrew J Grant, Mrutyunjay Suar, Wolf-Dietrich Hardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0045433&type=printable
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