Identification and Structural Characterization of an Unknown Trace Degradation Impurity in Cabazitaxel Injection by LC-DAD-SPE-NMR/MS

In this work, the hyphenated liquid chromatography-diode array detector-solid phase extraction-nuclear magnetic resonance/mass spectrometry (LC-DAD-SPE-NMR/MS) technique is employed to characterize a novel degradation impurity with an approximate content of 0.3%~0.4% in cabazitaxel injection. In LC...

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Bibliographic Details
Main Authors: LIU Hongbing, LIU Huili, LUO Liting, SUN Lijuan, CHEN Lei
Format: Article
Language:zho
Published: Science Press 2025-03-01
Series:Chinese Journal of Magnetic Resonance
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Online Access:http://121.43.60.238/bpxzz/article/2025/1000-4556/1000-4556-42-1-34.shtml
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