A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract
A 65-year-old Hispanic female presented with a one-year history of anorexia, nausea, early satiety, epigastric discomfort, and a 20 kg weight loss. Computed tomography (CT) demonstrated heterogeneous liver parenchyma. Upper endoscopy revealed large, fungating, infiltrative mass at the lesser gastric...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2020/1921805 |
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| author | Kathrin Dvir Gliceida M. Galarza-Fortuna Anna Willet Christopher Febres-Aldana Nathaly Cortez Samuel Rapaka Andre Coombs Robert Goldberg Michael Schwartz Kfir Ben-David |
| author_facet | Kathrin Dvir Gliceida M. Galarza-Fortuna Anna Willet Christopher Febres-Aldana Nathaly Cortez Samuel Rapaka Andre Coombs Robert Goldberg Michael Schwartz Kfir Ben-David |
| author_sort | Kathrin Dvir |
| collection | DOAJ |
| description | A 65-year-old Hispanic female presented with a one-year history of anorexia, nausea, early satiety, epigastric discomfort, and a 20 kg weight loss. Computed tomography (CT) demonstrated heterogeneous liver parenchyma. Upper endoscopy revealed large, fungating, infiltrative mass at the lesser gastric curvature incisura, highly suspicious of gastric tumor; however, initial biopsy of the gastric mass was equivocal and an exploratory laparoscopy was performed. Repeated intraoperative biopsies of the gastric mass and of liver parenchyma demonstrated diffuse hyalinized stroma consistent with amyloid deposition, and a bone marrow biopsy confirmed the diagnosis of primary light chain (AL) amyloidosis. |
| format | Article |
| id | doaj-art-47a4fb25f00a4bd88e496b54b38f927e |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-47a4fb25f00a4bd88e496b54b38f927e2025-02-03T01:01:27ZengWileyCase Reports in Surgery2090-69002090-69192020-01-01202010.1155/2020/19218051921805A Rare Case of Light Chain Amyloidosis of the Gastrointestinal TractKathrin Dvir0Gliceida M. Galarza-Fortuna1Anna Willet2Christopher Febres-Aldana3Nathaly Cortez4Samuel Rapaka5Andre Coombs6Robert Goldberg7Michael Schwartz8Kfir Ben-David9Department of Internal Medicine, Mount Sinai Medical Center, USADepartment of Internal Medicine, Mount Sinai Medical Center, USADepartment of Internal Medicine, Mount Sinai Medical Center, USAThe Arkadi M. Rywlin M.D. Department of Pathology, Mount Sinai Medical Center, USADepartment of Internal Medicine, Mount Sinai Medical Center, USADepartment of Internal Medicine, Mount Sinai Medical Center, USADepartment of General Surgery, Mount Sinai Medical Center, USADepartment of Gastroenterology, Mount Sinai Medical Center, USAComprehensive Cancer Center, Mount Sinai Medical Center, USADepartment of General Surgery, Mount Sinai Medical Center, USAA 65-year-old Hispanic female presented with a one-year history of anorexia, nausea, early satiety, epigastric discomfort, and a 20 kg weight loss. Computed tomography (CT) demonstrated heterogeneous liver parenchyma. Upper endoscopy revealed large, fungating, infiltrative mass at the lesser gastric curvature incisura, highly suspicious of gastric tumor; however, initial biopsy of the gastric mass was equivocal and an exploratory laparoscopy was performed. Repeated intraoperative biopsies of the gastric mass and of liver parenchyma demonstrated diffuse hyalinized stroma consistent with amyloid deposition, and a bone marrow biopsy confirmed the diagnosis of primary light chain (AL) amyloidosis.http://dx.doi.org/10.1155/2020/1921805 |
| spellingShingle | Kathrin Dvir Gliceida M. Galarza-Fortuna Anna Willet Christopher Febres-Aldana Nathaly Cortez Samuel Rapaka Andre Coombs Robert Goldberg Michael Schwartz Kfir Ben-David A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract Case Reports in Surgery |
| title | A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract |
| title_full | A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract |
| title_fullStr | A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract |
| title_full_unstemmed | A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract |
| title_short | A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract |
| title_sort | rare case of light chain amyloidosis of the gastrointestinal tract |
| url | http://dx.doi.org/10.1155/2020/1921805 |
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